Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610681 | 0.87 | KDM4E (0.42) | NOTUMKEAP1NFE2L2DAOALDH1A1 | |
| SCHEMBL12272939 | 0.85 | ALDH1A1 (0.46) | NOTUMKEAP1NFE2L2DAOALDH1A1 | |
| SCHEMBL12104561 | 0.78 | PKM (0.49) | GPR35DAOALDH1A1XDH | |
| SCHEMBL7248344 | 0.78 | DAO (0.57) | NOTUMKEAP1NFE2L2GPR35DAO | |
| SCHEMBL20894017 | 0.78 | GSK3B (0.39) | NOTUMGPR35DAOXDH | |
| SCHEMBL3607622 | 0.74 | GAA (0.42) | NOTUMALDH1A1KDM4EMAPT | |
| SCHEMBL21634045 | 0.74 | DAO (0.41) | NOTUMKEAP1NFE2L2GPR35DAO | |
| SCHEMBL15362171 | 0.74 | NOTUM (0.40) | NOTUMKEAP1NFE2L2GPR35DAO | |
| SCHEMBL741497 | 0.74 | KEAP1 (0.71) | NOTUMKEAP1NFE2L2GPR35DAO | |
| SCHEMBL3816299 | 0.73 | ALDH1A1 (0.44) | NOTUMKEAP1NFE2L2GPR35DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505204-A | Multifunctional flame-retardant anti-dripping copolyester and preparation method and application thereof | 四川大学 | 2025-02-25 | — | — | CN | disclosed |
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
| WO-2006092059-A1 | DESIGN AND SYNTHESIS OF NOVEL ANTIMICROBIALS | WU FAN (CA) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | NOTUM 2646/4885KEAP1 3254/4885NFE2L2 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.