Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328509 | 0.92 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL3326379 | 0.85 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL3601295 | 0.76 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL13299076 | 0.70 | MAPK8 (0.43) | AGTR1 | |
| SCHEMBL3324438 | 0.69 | AGTR1 (0.33) | AGTR1 | |
| SCHEMBL3328548 | 0.67 | AGTR1 (0.32) | AGTR1 | |
| SCHEMBL3328799 | 0.67 | AGTR1 (0.37) | AGTR1 | |
| SCHEMBL3329106 | 0.67 | PTGS2 (0.37) | AGTR1 | |
| SCHEMBL6047203 | 0.65 | PTGS2 (0.38) | — | |
| SCHEMBL3610158 | 0.65 | HSD17B1 (0.40) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | AGTR1 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.