Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601295 | 0.86 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL3328509 | 0.71 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL3597248 | 0.69 | HSD17B1 (0.59) | HSD17B1HSD17B2TRPM8MAPT | |
| SCHEMBL3607828 | 0.65 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL4602918 | 0.62 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL30743612 | 0.62 | ABCG2 (0.55) | AGTR1MAPT | |
| Ammonia Solution, Strong SCHEMBL28387773 | 0.62 | HSD17B1 (0.34) | HSD17B1 | |
| SCHEMBL2161550 | 0.61 | ABCG2 (0.41) | AGTR1MAPT | |
| SCHEMBL4638378 | 0.60 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL3873970 | 0.60 | AGTR1 (0.46) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
| WO-2006092059-A1 | DESIGN AND SYNTHESIS OF NOVEL ANTIMICROBIALS | WU FAN (CA) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | HSD17B1 3041/4885HSD17B2 3760/4885TRPM8 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.