Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247844 | 0.86 | ALDH1A1 (0.35) | ALDH1A1TSHRALOX15NQO2 | |
| SCHEMBL4674449 | 0.78 | CYP1A2 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8568142 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRALOX15 | |
| SCHEMBL10392936 | 0.73 | MB (0.33) | NQO2 | |
| SCHEMBL1586433 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRALOX15MEN1KMT2A | |
| SCHEMBL3608280 | 0.73 | EGLN1 (0.42) | ALDH1A1MAPTNQO2 | |
| SCHEMBL1586662 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRALOX15MEN1KMT2A | |
| SCHEMBL14438127 | 0.71 | LMNA (0.34) | ALDH1A1TSHRALOX15LMNA | |
| SCHEMBL7608160 | 0.71 | LMNA (0.33) | ALDH1A1TSHRALOX15MAPTTNF | |
| SCHEMBL11529648 | 0.71 | HPGD (0.40) | ALDH1A1TSHRALOX15MAPTTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156635-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS | GILLESPIE PAUL | 2009-06-18 | — | — | US | disclosed |
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156635-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS | GYS2, GYS1, GSK3A | ALDH1A1 633/4885TSHR 2818/4885ALOX15 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.