Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 5/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MST1R | Q04912 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618996 | 0.83 | HPGDS (0.39) | ALDH1A1F2GLAHPGDABL1 | |
| SCHEMBL3604542 | 0.78 | ALDH1A1 (0.35) | ALDH1A1F2GLAHPGDABL1 | |
| SCHEMBL3615306 | 0.78 | ALDH1A1 (0.44) | ALDH1A1F2GLAHPGDABL1 | |
| SCHEMBL3613074 | 0.77 | ALDH1A1 (0.46) | ALDH1A1F2GLAHPGDABL1 | |
| SCHEMBL534741 | 0.77 | ALDH1A1 (0.43) | ALDH1A1F2GLAHPGDABL1 | |
| SCHEMBL23247889 | 0.77 | PDE3B (0.46) | ALDH1A1F2GLAHPGDABL1 | |
| SCHEMBL18331443 | 0.76 | LDHA (0.58) | ALDH1A1LDHAPPARGPPARA | |
| SCHEMBL21057158 | 0.76 | LDHA (0.58) | ALDH1A1LDHAPPARGPPARA | |
| SCHEMBL3607774 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1F2GLAHPGDMET | |
| SCHEMBL3621503 | 0.75 | ALDH1A1 (0.41) | ALDH1A1F2GLAHPGDMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| EP-2139324-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | Syngeta Participations AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | ALDH1A1 350/4885F2 4394/4885GLA 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.