SCHEMBL3611287

SCHEMBL3611287

CC1=C(C)C(C)(C)C([Ti](Oc2ccccc2-c2ccccc2)(Oc2ccccc2-c2ccccc2)Oc2ccccc2-c2ccccc2)=C1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.35
ADRB2 P07550 4/20 0.33
L3MBTL1 Q9Y468 4/20 0.33
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
ADRB1 P08588 1/20 0.32
HRH1 P35367 1/20 0.32
ALDH1A1 P00352 5/20 0.32
KDM4E B2RXH2 3/20 0.31
FABP7 O15540 1/20 0.31
FABP3 P05413 1/20 0.31
FABP5 Q01469 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3676430 0.86 L3MBTL1 (0.35) HTR7ADRB2L3MBTL1MAPK1TDP1
SCHEMBL2841022 0.78 CA4 (0.31)
SCHEMBL3811401 0.74 CCNE2 (0.32)
SCHEMBL3811681 0.73 BACE1 (0.35) RAB9ASMN1; SMN2
SCHEMBL3624517 0.73 KDM4E (0.32) LMNAALDH1A1KDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL3625537 0.72 HTR7 (0.34) HTR7ADRB2L3MBTL1MAPK1TDP1
SCHEMBL370497 0.71 HTR7 (0.35) HTR7ADRB2L3MBTL1MAPK1TDP1
SCHEMBL627089 0.70 PDK2 (0.38)
SCHEMBL626368 0.70 PDK2 (0.38)
Hydrochloric Acid SCHEMBL346593 0.70 ADRA2A (0.34) HTR7ADRB2L3MBTL1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010576-B1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2013-07-24 EP disclosed
US-7645715-B2 Bis-arylaryloxy catalytic system for producing ethylene homopolymers or ethylene copolymers with alpha-olefins SK ENERGY CO., LTD. (KR) 2010-01-12 US disclosed
EP-2010576-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2009-01-07 EP disclosed
WO-2007123362-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-11-01 WO disclosed
US-20070249490-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK CORPORATION (KR) 2007-10-25 US disclosed