SCHEMBL3676430

SCHEMBL3676430

CC1=C(C)C(C)(C)C([Ti](Cl)(Cl)Oc2ccccc2-c2ccccc2)=C1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.35
MAPK1 P28482 3/20 0.35
LMNA P02545 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
HTR7 P34969 1/20 0.33
GAA P10253 1/20 0.33
ADRB2 P07550 3/20 0.32
RAB9A P51151 2/20 0.32
TP53 P04637 1/20 0.32
NCOA1 Q15788 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HTT P42858 2/20 0.32
ADRB1 P08588 1/20 0.31
HRH1 P35367 1/20 0.31
KDM4E B2RXH2 3/20 0.30
MAPT P10636 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3811401 0.87 CCNE2 (0.32)
SCHEMBL3811681 0.86 BACE1 (0.35) RAB9AMAPTSMN1; SMN2
SCHEMBL3611287 0.86 HTR7 (0.35) L3MBTL1MAPK1LMNATDP1HTR7
SCHEMBL626368 0.83 PDK2 (0.38)
SCHEMBL3681805 0.81 NUDT1 (0.32)
SCHEMBL3811684 0.81 HSD11B1 (0.36) ALDH1A1
SCHEMBL3769171 0.81 GRM4 (0.37) L3MBTL1LMNAGAARAB9ATP53
SCHEMBL618897 0.79
SCHEMBL3806063 0.76 BACE1 (0.34) MAPK1ALDH1A1
SCHEMBL3683551 0.74 NPC1 (0.31) LMNAALDH1A1KDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 EP disclosed
US-7833926-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK ENERGY CO., LTD. (KR) 2010-11-16 US disclosed
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK ENERGY CO., LTD. (KR) 2009-12-31 US disclosed
US-7589042-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK CORPORATION (KR) 2009-09-15 US disclosed
EP-1910427-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2008-04-16 EP disclosed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US disclosed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO disclosed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS ESR1, ERO1A, PPOX L3MBTL1 2232/4885MAPK1 1918/4885LMNA 4587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.