SCHEMBL361243

SCHEMBL361243

CCCCCCCC/C=C\CCCCCCCC(=O)C(O)(C(=O)CCCCCCC/C=C\CCCCCCCC)[C@@H](O)CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.58
CES1 P23141 2/20 0.58
DGKA P23743 1/20 0.52
TERT O14746 3/20 0.51
PTPN1 P18031 3/20 0.51
PPARG P37231 3/20 0.51
PPARD Q03181 3/20 0.51
PPARA Q07869 3/20 0.51
CYP1A2 P05177 2/20 0.51
MAPT P10636 2/20 0.51
CYP2C19 P33261 2/20 0.51
BLM P54132 2/20 0.51
HSD17B10 Q99714 2/20 0.51
FABP4 P15090 2/20 0.51
KMT2A Q03164 2/20 0.51
GMNN O75496 1/20 0.51
USP2 O75604 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
CYP2C9 P11712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8343681 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL8344661 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL8343680 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL19873069 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
Octane SCHEMBL16439984 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL2179345 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL2179341 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL170316 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL8344665 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1
SCHEMBL29709266 1.00 FAAH (0.58) FAAHCES1DGKATERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114302741-A Compositions and methods for treating autoimmune disorders 密执安大学评议会 2022-04-08 CN claimed
US-12428634-B2 Methods for extracting bioactive small RNAS from plants and mushrooms MIRNAGREEN S.R.L. (IT) 2025-09-30 US disclosed
CN-113454232-B Modulation of REP protein Activity in Closed End DNA (CEDNA) production 世代生物公司 2024-10-29 CN disclosed
US-20240344054-A1 IMPROVED METHOD FOR SMALL RNA PURIFICATION MIRNAGREEN S.R.L. (IT) 2024-10-17 US disclosed
CN-118489008-A Scalable and high purity cell-free synthesis of closed-end DNA vectors 世代生物公司 2024-08-13 CN disclosed
EP-4384612-A1 IMPROVED METHOD FOR SMALL RNA PURIFICATION Mirnagreen S.r.l. (IT) 2024-06-19 EP disclosed
CN-111867634-B Enhancement of translocation of micro/nanoparticles across mucus layers using alginate oligomers 阿尔吉法玛公司 2024-06-11 CN disclosed
US-11998539-B2 Substituted aminoquinolones as DGKalpha inhibitors for immune activation BAYER AKTIENGESELLSCHAFT (DE) 2024-06-04 US disclosed
CN-118043084-A Compositions and methods for metal-containing formulations capable of modulating immune responses 密执安大学评议会 2024-05-14 CN disclosed
CN-117940563-A Improved small RNA purification process 米尔纳格林有限责任公司 2024-04-26 CN disclosed
WO-2008148868-A1 PIPERIDINE/PIPERAZINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2008-12-11 WO disclosed
WO-2008148851-A1 PIPERIDINE/PIPERAZINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2008-12-11 WO disclosed
WO-2008148840-A1 PIPERIDINE/PIPERAZINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2008-12-11 WO disclosed
WO-2008148849-A2 PIPERIDINE/PIPERAZINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2008-12-11 WO disclosed
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors ASTRAZENECA AB (SE) 2008-04-24 US disclosed
EP-1893592-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS AstraZeneca AB (SE) 2008-03-05 EP disclosed
WO-2006134317-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2006-12-21 WO disclosed
US-6255095-B1 A NUCLEIC ACID THAT CODES FOR AN AMINO ACID SEQUENCE; THERAPY FOR RETINAL DEGENRATION UNIVERSITY OF UTAH RESEARCH FOUNDATION 2001-07-03 US disclosed
EP-0845981-A1 COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES GENZYME CORPORATION (US) 1998-06-10 EP disclosed
WO-1997046223-A1 COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES GENZYME CORPORATION (US) 1997-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11998539-B2 Substituted aminoquinolones as DGKalpha inhibitors for immune activation DGKK, DGKG, DGKA FAAH 2152/4885CES1 1267/4885DGKA 3/4885
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors DGAT1, DGAT2, GPR119 FAAH 962/4885CES1 147/4885DGKA 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.