Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119893 | 0.95 | ALDH1A1 (0.32) | ALDH1A1LMNATP53TSHRPTPN1 | |
| SCHEMBL18032045 | 0.91 | TRIM24 (0.33) | ALDH1A1LMNATP53TSHRPTPN1 | |
| SCHEMBL18032031 | 0.87 | TRIM24 (0.31) | TRIM24TRIM33 | |
| SCHEMBL18018647 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNATP53TSHRPTPN1 | |
| SCHEMBL13604642 | 0.78 | CA1 (0.31) | — | |
| SCHEMBL5643237 | 0.75 | ESR2 (0.30) | ESR2 | |
| SCHEMBL19015223 | 0.74 | — | — | |
| SCHEMBL510704 | 0.74 | TRIM24 (0.44) | ALDH1A1TRIM24TRIM33ESR2 | |
| SCHEMBL12917684 | 0.73 | — | — | |
| SCHEMBL19421004 | 0.73 | CYP3A4 (0.33) | LMNATP53TSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657230-B2 | Alkenyl dioxane compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657230-B2 | Alkenyl dioxane compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| US-20150184075-A1 | Liquid Crystal Composition Having Negative Dielectric Anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-07-02 | — | — | US | disclosed |
| US-20150184075-A1 | Liquid Crystal Composition Having Negative Dielectric Anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-07-02 | — | — | US | disclosed |
| US-8318718-B2 | Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318718-B2 | Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-20100125062-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | AMEN INC. (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100125062-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | AMEN INC. (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100105714-A1 | Furanone Compounds and Methods of Making and Using The Same | BIOGEN IDEC MA INC. (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100105714-A1 | Furanone Compounds and Methods of Making and Using The Same | BIOGEN IDEC MA INC. (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100105714-A1 | Furanone Compounds and Methods of Making and Using The Same | BIOGEN IDEC MA INC. (US) | 2010-04-29 | — | — | US | disclosed |
| EP-2121669-A2 | FURANONE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Biogen Idec MA, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008094574-A2 | FURANONE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008094574-A2 | FURANONE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| EP-1829876-A1 | NITROGENEOUS TRICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20060247266-A1 | Nitrogen-containing tricyclic compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | YBX1, PIEZO1, HAX1 | ALDH1A1 118/4885LMNA 619/4885TP53 4189/4885 |
| US-20060247266-A1 | Nitrogen-containing tricyclic compounds | MYO1B, CHRM1, MYL12A | ALDH1A1 3199/4885LMNA 768/4885TP53 3641/4885 |
| US-20100125062-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | PDE7A, PDE9A, PDE10A | ALDH1A1 640/4885LMNA 4732/4885TP53 4354/4885 |
| US-20100105714-A1 | Furanone Compounds and Methods of Making and Using The Same | ALK, ACVR1, ACVR1B | ALDH1A1 199/4885LMNA 1134/4885TP53 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.