Sugi Predict

Sugi Predict / Compounds / SCHEMBL36153

SCHEMBL36153

SCHEMBL36153

C=Cc1ccc(O[Si](C)(C)C(C)(C)C)c(O[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 1/20 0.42
▸ DRD2 P14416 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.33
▸ CA12 O43570 4/20 0.33
▸ CA1 P00915 4/20 0.33
▸ CA9 Q16790 4/20 0.33
▸ TP53 P04637 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ TSHR P16473 1/20 0.31
▸ KMT2A Q03164 2/20 0.30
▸ APP P05067 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25365134 0.92 TRPA1 (0.50) TRPA1DRD2ALDH1A1TDP1TSHR
SCHEMBL30540735 0.92 TRPA1 (0.50) TRPA1DRD2ALDH1A1TSHRKMT2A
SCHEMBL30540736 0.88 DRD2 (0.42) TRPA1DRD2ALDH1A1KMT2ASMN1; SMN2
SCHEMBL25366327 0.88 DRD2 (0.40) TRPA1DRD2ALDH1A1TDP1KMT2A
SCHEMBL30540734 0.85 DRD2 (0.38) TRPA1DRD2ALDH1A1TP53KMT2A
SCHEMBL25366465 0.85 KDM4E (0.40) TRPA1DRD2ALDH1A1TP53KMT2A
SCHEMBL30360260 0.83 ALDH1A1 (0.50) DRD2ALDH1A1TDP1TSHRMAPT
SCHEMBL36740 0.83 ALDH1A1 (0.50) DRD2ALDH1A1TDP1TSHRMAPT
SCHEMBL18035216 0.82 TRPA1 (0.47) TRPA1ALDH1A1TP53TDP1TSHR
SCHEMBL29519519 0.82 TRPA1 (0.47) TRPA1ALDH1A1TP53TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11117987-B2 Hydroxyaryl functionalized polymers BRIDGESTONE CORPORATION (JP) 2021-09-14 — — US disclosed
US-11028195-B2 Hydroxyaryl functionalized polymers BRIDGESTONE CORPORATION (JP) 2021-06-08 — — US disclosed
US-10843224-B2 Plasma deposition method for catechol/quinone functionalised layers LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) 2020-11-24 — — US disclosed
US-20190322777-A1 Hydroxyaryl Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2019-10-24 — — US disclosed
US-10392497-B2 Rubber compositions including siliceous fillers BRIDGESTONE CORPORATION (JP) 2019-08-27 — — US disclosed
US-10370475-B2 Elastomeric compounds having increased cold flow resistance and methods producing the same BRIDGESTONE CORPORATION (JP) 2019-08-06 — — US disclosed
US-20190233557-A1 Hydroxyaryl Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2019-08-01 — — US disclosed
US-10227425-B2 Hydroxyaryl functionalized polymers BRIDGESTONE CORPORATION (JP) 2019-03-12 — — US disclosed
US-20180079891-A1 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS BRIDGESTONE CORPORATION (JP) 2018-03-22 — — US disclosed
US-9868850-B2 Rubber compositions including siliceous fillers BRIDGESTONE CORPORATION (JP) 2018-01-16 — — US disclosed
US-20130035437-A1 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS BRIDGESTONE CORPORATION (JP) 2013-02-07 — — US disclosed
EP-2539394-A2 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS Bridgestone Corporation (JP) 2013-01-02 — — EP disclosed
US-20120136128-A1 ANIONIC POLYMERIZATION INITIATORS AND PROCESSES BRIDGESTONE CORPORATION (JP) 2012-05-31 — — US disclosed
EP-2448900-A2 ANIONIC POLYMERIZATION INITIATORS AND PROCESSES Bridgestone Corporation (JP) 2012-05-09 — — EP disclosed
US-20120065315-A1 ELASTOMERIC COMPOUNDS HAVING INCREASED COLD FLOW RESISTANCE AND METHODS PRODUCING THE SAME BRIDGESTONE CORPORATION (JP) 2012-03-15 — — US disclosed
WO-2011106765-A2 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS BRIDGESTONE CORPORATION (JP) 2011-09-01 — — WO disclosed
WO-2011008501-A2 ANIONIC POLYMERIZATION INITIATORS AND PROCESSES BRIDGESTONE CORPORATION (JP) 2011-01-20 — — WO disclosed
US-20100286348-A1 HYDROXYARYL FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2010-11-11 — — US disclosed
EP-2231719-A2 HYDROXYARYL FUNCTIONALIZED POLYMERS Bridgestone Corporation (JP) 2010-09-29 — — EP disclosed
WO-2009086490-A2 HYDROXYARYL FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2009-07-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190322777-A1 Hydroxyaryl Functionalized Polymers HAAO, HCAR3, VCL TRPA1 2659/4885DRD2 2226/4885ALDH1A1 564/4885
US-11028195-B2 Hydroxyaryl functionalized polymers HAAO, HCAR3, VCL TRPA1 2609/4885DRD2 2289/4885ALDH1A1 667/4885
US-10227425-B2 Hydroxyaryl functionalized polymers HAAO, HCAR3, VCL TRPA1 2659/4885DRD2 2226/4885ALDH1A1 564/4885
US-20120136128-A1 ANIONIC POLYMERIZATION INITIATORS AND PROCESSES AP1M1, AP2M1, CCNE2 TRPA1 570/4885DRD2 2404/4885ALDH1A1 830/4885
US-20100286348-A1 HYDROXYARYL FUNCTIONALIZED POLYMERS HAAO, HCAR3, VCL TRPA1 2659/4885DRD2 2226/4885ALDH1A1 564/4885
US-11117987-B2 Hydroxyaryl functionalized polymers HAAO, HCAR3, VCL TRPA1 2659/4885DRD2 2226/4885ALDH1A1 564/4885
US-20190233557-A1 Hydroxyaryl Functionalized Polymers HAAO, HCAR3, VCL TRPA1 2609/4885DRD2 2289/4885ALDH1A1 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.