Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3615425

CC1=C(C)C(C)(C)C([Ti+2]Oc2ccccc2C)=C1C.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL392238 0.82
Hydrochloric Acid SCHEMBL3625537 0.82 HTR7 (0.34) MEN1RAB9AKMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL4461086 0.80 CA4 (0.30)
Hydrochloric Acid SCHEMBL394796 0.71 TSHR (0.31) TSHR
Hydrochloric Acid SCHEMBL715987 0.69
Hydrochloric Acid SCHEMBL4359909 0.69
Hydrochloric Acid SCHEMBL7112713 0.68 TSHR (0.45) MEN1NPC1TSHRRAB9AKMT2A
Hydrochloric Acid SCHEMBL3672197 0.68 MEN1 (0.33) MEN1NPC1TSHRRAB9AKMT2A
Bromide SCHEMBL7112211 0.66 TSHR (0.46) MEN1NPC1TSHRRAB9AKMT2A
Hydrochloric Acid SCHEMBL8461817 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010576-B1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2013-07-24 EP disclosed
US-7645715-B2 Bis-arylaryloxy catalytic system for producing ethylene homopolymers or ethylene copolymers with alpha-olefins SK ENERGY CO., LTD. (KR) 2010-01-12 US disclosed
EP-2010576-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2009-01-07 EP disclosed
WO-2007123362-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-11-01 WO disclosed
US-20070249490-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK CORPORATION (KR) 2007-10-25 US disclosed