Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 4/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.39 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609410 | 0.90 | CDK9 (0.49) | ROCK2CDC7MAP4K4CDK2MAPKAPK2 | |
| SCHEMBL3618175 | 0.89 | TBK1 (0.45) | ROCK2ROCK1CDC42BPBKCNMA1TBK1 | |
| Hydrochloric Acid SCHEMBL3617474 | 0.89 | CDK9 (0.48) | ROCK2CDC7MAP4K4CDK2MAPKAPK2 | |
| SCHEMBL3617304 | 0.87 | KCNMA1 (0.44) | ROCK2CDC7MAP4K4CDK2MAPKAPK2 | |
| SCHEMBL3615497 | 0.87 | KCNMA1 (0.48) | ROCK2CDC7MAP4K4CDK2MAPKAPK2 | |
| SCHEMBL3608996 | 0.86 | CDC7 (0.38) | ROCK2CDC7MAP4K4CDK2MAPKAPK2 | |
| SCHEMBL13408151 | 0.81 | NR1H2 (0.44) | TBK1KMT2A | |
| SCHEMBL14283679 | 0.81 | CDC7 (0.42) | ROCK2CDC7MAP4K4CDK2MAPKAPK2 | |
| SCHEMBL3616822 | 0.80 | NR1H2 (0.47) | TBK1 | |
| SCHEMBL3617867 | 0.77 | RET (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105664-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100105664-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100105664-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105664-A1 | ORGANIC COMPOUNDS | SLCO1B3, SLCO1B1, SLC10A6 | ROCK2 3665/4885CDC7 4089/4885MAP4K4 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.