Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.63 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615074 | 0.86 | HSP90AA1 (0.50) | HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL3622064 | 0.82 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1 | |
| SCHEMBL3621474 | 0.80 | NPC1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL23978825 | 0.79 | ALDH1A1 (0.49) | HSP90AA1HSP90B1 | |
| SCHEMBL3624299 | 0.79 | HSP90AA1 (0.52) | HSP90AA1HSP90B1 | |
| SCHEMBL3611841 | 0.79 | MMP13 (0.52) | HSP90AA1HSP90AB1 | |
| SCHEMBL3619586 | 0.78 | LMNA (0.51) | HSP90AA1 | |
| SCHEMBL3625227 | 0.78 | HSP90AA1 (0.41) | HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL20767541 | 0.78 | HSP90AA1 (1.00) | HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL20767512 | 0.78 | HSP90AA1 (0.75) | HSP90AA1HSP90B1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781485-B2 | Hsp90 family protein inhibitors | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20070265268-A1 | Hsp90 Family protein Inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1813270-A1 | HSP90 FAMILY PROTEIN INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265268-A1 | Hsp90 Family protein Inhibitors | HSPA4L, HSP90AB1, HSP90B1 | HSP90AA1 4/4885HSP90B1 3/4885HSP90AB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.