Adenine

Adenine

SCHEMBL3619794

NP(O)O.Nc1ncnc2[nH]cnc12

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 4/20 0.41
PI4K2B Q8TCG2 4/20 0.41
PI4K2A Q9BTU6 4/20 0.41
PI4KB Q9UBF8 4/20 0.41
XDH P47989 2/20 0.41
LRRK2 Q5S007 2/20 0.41
LMNA P02545 1/20 0.41
DRD3 P35462 1/20 0.41
ADORA2A P29274 2/20 0.35
ADORA1 P30542 2/20 0.35
RET P07949 1/20 0.33
ERAP1 Q9NZ08 1/20 0.33
GDA Q9Y2T3 1/20 0.33
AHCY P23526 3/20 0.31
PIK3CG P48736 1/20 0.30
MTAP Q13126 1/20 0.30
PNP P00491 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL20485928 0.92 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL385841 0.90 PI4KA (0.45) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3416954 0.90 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3413247 0.90 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3414603 0.90 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL8110 0.90 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL1871837 0.88 PI4KA (0.44) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL691914 0.88 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL5601016 0.88 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL11798390 0.88 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684382-A Preparation method of long-chain oligonucleotide 苏州欧利生物医药科技有限公司 2025-03-25 CN disclosed
WO-2024006672-A2 MODIFIED GUIDE RNAS FOR CRISPR GENOME EDITING UNIVERSITY OF MASSACHUSETTS (US) 2024-01-04 WO disclosed
CN-115666659-A Synthesis of modified oligonucleotides with increased stability 马萨诸塞大学 2023-01-31 CN disclosed
US-20170003289-A1 METHODS AND MATERIALS FOR ASSESSING ENZYME-NUCLEIC ACID COMPLEXES MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2017-01-05 US disclosed
US-20100273681-A1 COMBINATORIAL CHEMISTRY REACTION CELL WITH OPTICAL TWEEZERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-10-28 US disclosed
US-20060008907-A1 Control of gene expression via light activated RNA interference THE CURATORS OF THE UNIVERSITY OF MISSOURI 2006-01-12 US disclosed
US-6855501-B2 Transfer of arrayed chemical compositions LINDEN TECHNOLOGIES, INC. (US) 2005-02-15 US disclosed
EP-1154857-A4 SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR AUTOMATED FLUID OR GAS DELIVERY INVITROGEN CORP (US) 2005-01-19 EP disclosed
US-6838447-B2 Particulate compositions for chemical synthesis LINDEN TECHNOLOGIES, INC. (US) 2005-01-04 US disclosed
EP-0791238-B1 LIQUID DISTRIBUTION SYSTEM ORCHID BIOSCIENCES INC (US) 2004-09-22 EP disclosed
US-20020136772-A1 Polymer synthesis LINDEN TECHNOLOGIES, INC. 2002-09-26 US disclosed
EP-1154857-A1 SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR AUTOMATED FLUID OR GAS DELIVERY INVITROGEN CORPORATION (US) 2001-11-21 EP disclosed
WO-2000045957-A1 SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR AUTOMATED FLUID OR GAS DELIVERY INVITROGEN CORPORATION (US) 2000-08-10 WO disclosed
US-6033544-A Liquid distribution system SARNOFF CORPORATION (US) 2000-03-07 US disclosed
US-5958344-A System for liquid distribution SARNOFF CORPORATION (US) 1999-09-28 US disclosed
US-5846396-A Liquid distribution system SARNOFF CORPORATION (US) 1998-12-08 US disclosed
EP-0791238-A4 LIQUID DISTRIBUTION SYSTEM SARNOFF DAVID RES CENTER (US) 1998-09-02 EP disclosed
EP-0791238-A1 LIQUID DISTRIBUTION SYSTEM Sarnoff Corporation (US) 1997-08-27 EP disclosed
WO-1996015576-A9 LIQUID DISTRIBUTION SYSTEM 1996-08-29 WO disclosed
WO-1996015576-A1 LIQUID DISTRIBUTION SYSTEM DAVID SARNOFF RESEARCH CENTER, INC. (US) 1996-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170003289-A1 METHODS AND MATERIALS FOR ASSESSING ENZYME-NUCLEIC ACID COMPLEXES RNGTT, DNASE1, POLRMT PI4KA 4095/4885PI4K2B 4111/4885PI4K2A 3887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.