Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136297 | 0.80 | CA1 (0.54) | ALDH1A1HTTTP53SMN1; SMN2CA12 | |
| SCHEMBL472284 | 0.79 | TSHR (0.50) | ALDH1A1TP53TSHRSMN1; SMN2CA12 | |
| Terephthalic Acid SCHEMBL11564620 | 0.78 | TSHR (0.60) | ALDH1A1HTTTP53TSHRSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL2160594 | 0.78 | TSHR (0.60) | ALDH1A1HTTTP53TSHRSMN1; SMN2 | |
| SCHEMBL925065 | 0.76 | TSHR (0.52) | ALDH1A1TP53TSHRSMN1; SMN2CA12 | |
| SCHEMBL28137613 | 0.75 | MEN1 (0.57) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| Terephthalic Acid SCHEMBL1482407 | 0.75 | TSHR (0.71) | ALDH1A1TP53TSHRSMN1; SMN2CA12 | |
| Butane SCHEMBL2586584 | 0.75 | NPC1 (0.67) | ALDH1A1TP53TSHRSMN1; SMN2CA12 | |
| SCHEMBL29114272 | 0.74 | MEN1 (0.47) | ALDH1A1HTTTP53TSHRSMN1; SMN2 | |
| SCHEMBL472318 | 0.73 | HCAR3 (0.57) | ALDH1A1TP53TSHRSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600224-B1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2026-05-06 | — | — | EP | claimed |
| EP-3099284-B1 | OIL-IN-WATER EMULSION SUNSCREEN COMPOSITION | ISP INVESTMENTS LLC (US) | 2021-07-28 | — | — | EP | claimed |
| EP-2274324-B1 | SUBSTANCES AND COMPOSITIONS FOR ENHANCING DNA REPAIR AND METHODS OF USE | UNIV CORNELL (US) | 2014-08-06 | — | — | EP | claimed |
| EP-2379625-B1 | UV AND LIGHT PROTECTIVE FILM | HUHTAMAKI FORCHHEIM (DE) | 2013-02-20 | — | — | EP | claimed |
| EP-1844106-B1 | SILOXANES COMPRISING GUANIDINO GROUPS AND USE THEREOF FOR COSMETIC FORMULATIONS | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-07-11 | — | — | EP | claimed |
| US-7825207-B2 | Siloxanes containing guanidino groups and use thereof for cosmetic formulations | GOLDSCHMIDT GMBH (DE) | 2010-11-02 | — | — | US | claimed |
| EP-1688453-B1 | UV light absorbing quaternary polysiloxanes | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-07-23 | — | — | EP | claimed |
| US-20060188455-A1 | Siloxanes containing guanidino groups and use thereof for cosmetic formulations | EVONIK DEGUSSA GMBH (DE) | 2006-08-24 | — | — | US | claimed |
| US-20060188456-A1 | UV-light-absorbing quaternary polysiloxanes | EVONIK DEGUSSA GMBH (DE) | 2006-08-24 | — | — | US | claimed |
| EP-1688453-A1 | UV light absorbing quaternary polysiloxanes | Goldschmidt GmbH (DE) | 2006-08-09 | — | — | EP | claimed |
| EP-1285943-B1 | Uv-absorbing quaternary polysiloxanes | GOLDSCHMIDT GMBH (DE) | 2005-10-19 | — | — | EP | claimed |
| US-6630132-B2 | Textile care and cosmetic preparations; quaternization by reacting polysiloxane with a tertiary amine | GOLDSCHMIDT AG (DE) | 2003-10-07 | — | — | US | claimed |
| US-20030108494-A1 | UV-light-absorbing quaternary polysiloxanes | GOLDSCHMIDT AG (DE) | 2003-06-12 | — | — | US | claimed |
| EP-1285943-A2 | Uv-absorbing quaternary polysiloxanes | Goldschmidt AG (DE) | 2003-02-26 | — | — | EP | claimed |
| EP-0761201-B1 | Ultraviolet radiation absorption composition | ROHM & HAAS (US) | 2002-01-09 | — | — | EP | claimed |
| US-20120248758-A1 | SECURITY DOCUMENT | THE GOVERNOR & COMPANY OF THE BANK OF ENGLAND (GB) | 2012-10-04 | — | — | US | disclosed |
| US-7776989-B2 | UV-light-absorbing quaternary polysiloxanes | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20030108494-A1 | UV-light-absorbing quaternary polysiloxanes | GOLDSCHMIDT AG (DE) | 2003-06-12 | — | — | US | disclosed |
| EP-1285943-A2 | Uv-absorbing quaternary polysiloxanes | Goldschmidt AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2002100958-A1 | AQUEOUS COATING COMPOSITION CONTAINING UV RADIATION ABSORBING AGENTS | RHODIA CHIMIE (FR) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060188455-A1 | Siloxanes containing guanidino groups and use thereof for cosmetic formulations | UNG, GMPS, GLA | ALDH1A1 354/4885HTT 3305/4885TP53 2767/4885 |
| US-20060188456-A1 | UV-light-absorbing quaternary polysiloxanes | UBE2I, UFL1, ERCC4 | ALDH1A1 635/4885HTT 894/4885TP53 1073/4885 |
| US-20030108494-A1 | UV-light-absorbing quaternary polysiloxanes | CUTA, XRCC5, XRCC6 | ALDH1A1 615/4885HTT 268/4885TP53 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.