Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364251 | 0.88 | MEN1 (0.35) | GPBAR1FFAR1FFAR4 | |
| SCHEMBL365274 | 0.85 | GPBAR1 (0.46) | GPBAR1POLBTDP1 | |
| SCHEMBL363355 | 0.83 | FFAR1 (0.38) | CNR1GPBAR1FFAR1FFAR4PLA2G4A | |
| SCHEMBL363356 | 0.83 | FFAR1 (0.38) | CNR1GPBAR1FFAR1FFAR4PLA2G4A | |
| SCHEMBL363178 | 0.83 | GPBAR1 (0.51) | GPBAR1PPARGPOLBTDP1 | |
| SCHEMBL370059 | 0.82 | GPBAR1 (0.35) | GPBAR1FFAR1TDP1 | |
| SCHEMBL365756 | 0.82 | ADRB3 (0.38) | GPBAR1PPARGPOLB | |
| SCHEMBL12505651 | 0.81 | GPBAR1 (0.35) | GPBAR1 | |
| SCHEMBL363628 | 0.81 | ADRB1 (0.35) | GPBAR1FFAR1POLBTDP1 | |
| SCHEMBL362796 | 0.80 | GPBAR1 (0.39) | GPBAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |