Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363394 | 0.89 | MRGPRX4 (0.40) | ADRB3GPBAR1MRGPRX4ADRB1PPARG | |
| SCHEMBL370059 | 0.89 | GPBAR1 (0.35) | ADRB3GPBAR1ADRB1P2RX3 | |
| SCHEMBL363628 | 0.88 | ADRB1 (0.35) | ADRB3GPBAR1ADRB1POLBP2RX3 | |
| SCHEMBL365274 | 0.87 | GPBAR1 (0.46) | GPBAR1MRGPRX4POLBMEN1KMT2A | |
| SCHEMBL369888 | 0.85 | KDR (0.38) | GPBAR1MRGPRX4AKR1C3POLBPPARG | |
| SCHEMBL363178 | 0.85 | GPBAR1 (0.51) | ADRB3GPBAR1ADRB1POLBPPARG | |
| SCHEMBL364384 | 0.83 | P2RX3 (0.41) | ADRB3GPBAR1MRGPRX4KMOPOLB | |
| SCHEMBL364385 | 0.83 | P2RX3 (0.41) | ADRB3GPBAR1MRGPRX4KMOPOLB | |
| SCHEMBL362064 | 0.82 | CNR1 (0.37) | GPBAR1POLBPPARG | |
| SCHEMBL363623 | 0.81 | GPBAR1 (0.39) | GPBAR1MRGPRX4KMOAKR1C3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |