SCHEMBL3621168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14856243	0.87	BLM (0.47)	LMNAMAPK1HTTRAB9AACHE
	SCHEMBL10618539	0.86	ACHE (0.59)	MAPK1ACHELDHABLMNPSR1
	SCHEMBL30536168	0.83	BLM (0.64)	LMNAMAPK1HTTRAB9AFFAR1
	SCHEMBL3667658	0.83	PTGS2 (0.61)	LMNAMAPK1HTTRAB9ATSHR
	SCHEMBL3817028	0.82	LMNA (0.54)	LMNAMAPK1HTTRAB9AFFAR1
	SCHEMBL9513688	0.80	FFAR1 (0.56)	LMNAMAPK1HTTRAB9AFFAR1
	SCHEMBL16798294	0.78	LMNA (0.47)	LMNAMAPK1HTTRAB9AFFAR1
	SCHEMBL4513011	0.78	CES2 (0.50)	LMNATSHRAPPCYP2C19PTGS2
	SCHEMBL20379539	0.78	FFAR1 (0.57)	LMNAMAPK1HTTRAB9AFFAR1
	SCHEMBL7978440	0.77	GRM8 (0.54)	RAB9ATSHRTUBB1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.