SCHEMBL3621623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3621561	0.86	MTNR1A (0.48)	MTNR1ACYP19A1CYP2C19CYP3A4CYP2C9
	SCHEMBL7289069	0.77	ALDH1A1 (0.53)	CYP2C19HDAC6MAOBCA12CA9
	7-(2-Butynyloxy)Coumarin SCHEMBL17682923	0.77	MTNR1A (0.77)	MTNR1ACYP1A2MAOAMAOBCA12
	SCHEMBL3619696	0.76	MTNR1A (0.45)	MTNR1ACYP19A1CYP2C19CYP3A4CYP2C9
	SCHEMBL3619684	0.75	SLC2A1 (0.56)	MTNR1ACYP19A1CYP2C19CYP3A4CYP2C9
	SCHEMBL3617868	0.73	MAOB (0.62)	MTNR1AMAOAMAOBCA12CA9
	SCHEMBL3618379	0.73	NPC1 (0.40)	MTNR1ACYP19A1CYP2C19CYP3A4CYP2C9
	SCHEMBL14364687	0.72	MAOB (0.52)	MTNR1ACYP3A4CYP1A2HDAC6MAOA
	SCHEMBL3619676	0.72	CYP19A1 (0.42)	MTNR1ACYP19A1CYP2C19CYP3A4CYP2C9
	SCHEMBL3615496	0.71	LTA4H (0.47)	MTNR1ACYP19A1HDAC6MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.