Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362146 | 0.74 | RAPGEF4 (0.39) | TSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL3693870 | 0.71 | KMT2A (0.50) | TSHRMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL7698213 | 0.71 | TSHR (0.48) | TSHRMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL13990206 | 0.71 | TSHR (0.48) | TSHRMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11932674 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL11216375 | 0.67 | TSHR (0.32) | TSHR | |
| SCHEMBL14037004 | 0.67 | TSHR (0.44) | TSHRMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9638465 | 0.67 | ALDH1A1 (0.52) | TSHRMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL16359030 | 0.67 | TSHR (0.44) | TSHRMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL361279 | 0.67 | ALDH1A1 (0.50) | TSHRMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311112-B1 | ELECTRONIC DEVICES COMPRISING METAL COMPLEXES HAVING ISONITRILE LIGANDS | MERCK PATENT GMBH (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-20110101327-A1 | Electronic Devices Comprising Metal Complexes Having Isonitrile Ligands | MERCK PATENT GMBH (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110101327-A1 | Electronic Devices Comprising Metal Complexes Having Isonitrile Ligands | EXOC4, ICMT, NCLN | TSHR 4338/4885MAPT 1038/4885ALDH1A1 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.