Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19386740 | 0.79 | KMT2A (0.36) | RAPGEF4KDM4EKMT2A | |
| SCHEMBL17133540 | 0.78 | L3MBTL1 (0.40) | ALDH1A1KDM4EMAPTTSHRMEN1 | |
| SCHEMBL11932674 | 0.77 | MEN1 (0.30) | MEN1KMT2AHSP90AA1ATM | |
| SCHEMBL3286340 | 0.75 | MEN1 (0.48) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL3286343 | 0.75 | MEN1 (0.48) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL502928 | 0.75 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL961129 | 0.74 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL362368 | 0.74 | TSHR (0.39) | ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL6377762 | 0.73 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL13154687 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10620143-B2 | Sensor and method of detecting an analyte using 19F NMR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-04-14 | — | — | US | disclosed |
| EP-3369845-B1 | ACTIVE CONTAINING FIBROUS STRUCTURES WITH MULTIPLE REGIONS HAVING DIFFERING DENSITIES | PROCTER & GAMBLE (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2800802-B1 | ACTIVE CONTAINING FIBROUS STRUCTURES WITH MULTIPLE REGIONS HAVING DIFFERING DENSITIES | PROCTER & GAMBLE (US) | 2018-02-28 | — | — | EP | disclosed |
| US-9772568-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-09-26 | — | — | US | disclosed |
| US-9772568-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-09-26 | — | — | US | disclosed |
| US-20160291489-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20160291489-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-06 | — | — | US | disclosed |
| US-8895781-B2 | Transition metal-catalyzed C—H amination using unactivated amines | GEORGETOWN UNIVERSITY (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2311112-B1 | ELECTRONIC DEVICES COMPRISING METAL COMPLEXES HAVING ISONITRILE LIGANDS | MERCK PATENT GMBH (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-20110213146-A1 | Transition Metal-Catalyzed C-H Amination Using Unactivated Amines | GEORGETOWN UNIVERSITY (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110101327-A1 | Electronic Devices Comprising Metal Complexes Having Isonitrile Ligands | MERCK PATENT GMBH (DE) | 2011-05-05 | — | — | US | disclosed |
| WO-2010015307-A1 | ELECTRONIC DEVICES COMPRISING METAL COMPLEXES HAVING ISONITRILE LIGANDS | MERCK PATENT GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110101327-A1 | Electronic Devices Comprising Metal Complexes Having Isonitrile Ligands | EXOC4, ICMT, NCLN | RAPGEF4 199/4885ALDH1A1 2323/4885KDM4E 3403/4885 |
| US-20110213146-A1 | Transition Metal-Catalyzed C-H Amination Using Unactivated Amines | AOC3, AOC2, MPO | RAPGEF4 2154/4885ALDH1A1 2510/4885KDM4E 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.