Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363851 | 0.86 | POLB (0.32) | — | |
| SCHEMBL364814 | 0.78 | KCNN4 (0.43) | RAB9ANPC1ALDH1A1S1PR4S1PR2 | |
| SCHEMBL363771 | 0.78 | NPC1 (0.42) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL362592 | 0.76 | KCNN4 (0.37) | RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL364833 | 0.75 | KCNN4 (0.36) | RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL363549 | 0.73 | NPC1 (0.34) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL363211 | 0.73 | NPC1 (0.34) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL364193 | 0.73 | NPC1 (0.34) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL14965778 | 0.72 | RAB9A (0.37) | RAB9ANPC1MAPTTP53 | |
| SCHEMBL14965530 | 0.72 | RAB9A (0.37) | RAB9ANPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |