SCHEMBL3625367

SCHEMBL3625367

CC(C)(C)Cc1cc(-c2ccc(Cl)cc2S(=O)(=O)O)c(S(=O)(=O)O)c(CC(C)(C)C)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 2/20 0.32
PSEN2 P49810 2/20 0.32
APH1B Q8WW43 2/20 0.32
NCSTN Q92542 2/20 0.32
APH1A Q96BI3 2/20 0.32
PSENEN Q9NZ42 2/20 0.32
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ESR1 P03372 1/20 0.30
TP53 P04637 1/20 0.30
PGR P06401 1/20 0.30
CYP3A4 P08684 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
AR P10275 1/20 0.30
MAPT P10636 1/20 0.30
DRD1 P21728 1/20 0.30
PTGS1 P23219 1/20 0.30
SLC6A2 P23975 1/20 0.30
PDE4A P27815 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196568 0.73 S100A4 (0.48) USP2TP53
SCHEMBL2156081 0.72 NSD2 (0.33)
SCHEMBL3695968 0.72 S100A4 (0.46) USP2TP53
SCHEMBL3696775 0.72 S100A4 (0.46) USP2TP53
SCHEMBL3699050 0.72 S100A4 (0.46) USP2TP53
SCHEMBL4301050 0.72 S100A4 (0.46) USP2TP53
SCHEMBL3625366 0.71 CYP2C9 (0.31)
SCHEMBL13873006 0.65 CCR2 (0.41) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2742906 0.64 S100A4 (0.42) PTGS1
SCHEMBL3389667 0.63 L3MBTL1 (0.38) CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2503629-A1 MEMBRANE ELECTRODE ASSEMBLY AND FUEL CELL USING SAME Sumitomo Chemical Company, Limited (JP) 2012-09-26 EP disclosed
EP-2233459-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-09-29 EP disclosed