Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624139 | 0.76 | GPR35 (0.36) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL997481 | 0.75 | ADORA2A (0.33) | ALDH1A1NPC1NPSR1POLBMEN1 | |
| SCHEMBL3627208 | 0.74 | TDO2 (0.51) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL13226974 | 0.74 | RAC1 (0.32) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL313693 | 0.74 | CTSS (0.38) | ALDH1A1HSD17B10KDM4ETSHRL3MBTL1 | |
| SCHEMBL3625396 | 0.73 | HTT (0.36) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL3624833 | 0.73 | ENPP3 (0.43) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL16064009 | 0.73 | TDO2 (0.33) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL996497 | 0.72 | CCR1 (0.42) | MAPTNPC1RAB9ALMNAMEN1 | |
| SCHEMBL3659800 | 0.71 | MEN1 (0.34) | ALDH1A1HPGDHSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033466-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE | PHENOMIX CORPORATION (US) | 2010-03-25 | — | — | WO | disclosed |