SCHEMBL996497

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL997481	0.85	ADORA2A (0.33)	TDO2MGAMGAASIMGAM2
	SCHEMBL3627208	0.81	TDO2 (0.51)	ADORA1TDO2IDO1MEN1KMT2A
	SCHEMBL2843197	0.79	CCR1 (0.39)	CCR1CCR8CYP1A1CYP1A2CYP1B1
	SCHEMBL3625396	0.78	HTT (0.36)	CYP1A2GAANPC1RAB9AMEN1
	SCHEMBL3624833	0.78	ENPP3 (0.43)	TDO2IDO1GAANPC1RAB9A
	SCHEMBL3663254	0.78	KDM4E (0.37)	TDO2IDO1GAANPC1RAB9A
	SCHEMBL6809754	0.77	KDM4E (0.46)	CCR1CCR8NPC1RAB9AMEN1
	SCHEMBL3625504	0.77	MAPT (0.40)	CYP1A1CYP1A2CYP1B1GAANPC1
	SCHEMBL3659800	0.76	MEN1 (0.34)	TDO2IDO1GAAMEN1KMT2A
	SCHEMBL8140229	0.75	CCR1 (0.40)	CCR1CCR8CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.