Propionic Acid

Propionic Acid

SCHEMBL3625516

CCC(=O)O.c1c[nH]nn1.c1c[nH]nn1.c1c[nH]nn1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL1242832 0.89 FFAR3 (0.34) FFAR3
Malonic Acid SCHEMBL27973934 0.84 LDHA (0.41)
Glycolic Acid SCHEMBL21635478 0.84
Acetic Acid SCHEMBL9630666 0.84 FFAR3 (0.35) FFAR3
Bicarbonate SCHEMBL5682507 0.84
Bicarbonate SCHEMBL1563325 0.84
Thioglycolic Acid SCHEMBL28058106 0.83
SCHEMBL28860134 0.82 TSHR (0.34)
Acetone SCHEMBL4541424 0.81
Benzene SCHEMBL29022973 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004043-A1 CRYPTOPHANE DERIVATIVES AND METHODS OF USE THEREOF GEORGETOWN UNIVERISTY (US) 2014-01-02 US disclosed
US-8222022-B2 Tri-functionalized cryptophane biosensors THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2012-07-17 US disclosed
WO-2012051323-A2 CRYPTOPHANE DERIVATIVES AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY (US) 2012-04-19 WO disclosed
US-20100105099-A1 TRI-FUNCTIONALIZED CRYPTOPHANE, SYNTHESIS AND USES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105099-A1 TRI-FUNCTIONALIZED CRYPTOPHANE, SYNTHESIS AND USES THEREOF SPR, CACYBP, CRY2 FFAR3 1883/4885
US-20140004043-A1 CRYPTOPHANE DERIVATIVES AND METHODS OF USE THEREOF CRY2, CRY1, CRYAB FFAR3 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.