Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 11/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21229776 | 0.83 | KCNN4 (0.45) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6967423 | 0.76 | KCNN4 (0.43) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL27902048 | 0.76 | KCNN4 (0.43) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL363513 | 0.75 | KMT2A (0.56) | MAPTKMT2A | |
| SCHEMBL6326377 | 0.74 | CYP1A2 (0.53) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6326382 | 0.74 | CYP1A2 (0.53) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1627216 | 0.73 | AKR1C3 (0.64) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL31294792 | 0.73 | KCNN4 (0.46) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL362789 | 0.73 | CES2 (0.50) | CES2MAPTKMT2A | |
| SCHEMBL28091068 | 0.72 | MEN1 (0.41) | KCNN4HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593424-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | Medeia Therapeutics Ltd (FI) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007644-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | MEDEIA THERAPEUTICS LTD (FI) | 2012-01-19 | — | — | WO | claimed |