SCHEMBL3625922

SCHEMBL3625922

O=C1OC2(c3ccccc31)c1ccc(O)c(I)c1Oc1c2cc(I)c(O)c1I

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.86
KMT2A Q03164 6/20 0.86
TDP1 Q9NUW8 5/20 0.86
RECQL P46063 3/20 0.86
BLM P54132 3/20 0.86
THRB P10828 2/20 0.86
ACE2 Q9BYF1 2/20 0.86
L3MBTL1 Q9Y468 2/20 0.86
USP2 O75604 2/20 0.86
CDK2 P24941 1/20 0.86
CHAT P28329 1/20 0.86
BLVRB P30043 1/20 0.86
RXFP1 Q9HBX9 1/20 0.86
GNG2 P59768 1/20 0.65
GNB1 P62873 1/20 0.65
PRMT1 Q99873 2/20 0.54
GLB1 P16278 1/20 0.51
CTRC Q99895 1/20 0.51
CXCR1 P25024 1/20 0.50
AVPR2 P30518 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30160637 1.00 MEN1 (0.86) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL29353687 0.93 MEN1 (1.00) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL25042 0.93 MEN1 (1.00) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL29356181 0.93 MEN1 (1.00) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL250944 0.92 MEN1 (0.97) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL3686955 0.92 MEN1 (0.97) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL1461335 0.92 MEN1 (0.97) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL18526925 0.92 MEN1 (0.97) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL29827300 0.92 MEN1 (0.97) MEN1KMT2ATDP1RECQLBLM
Erythrosine SCHEMBL4856858 0.92 MEN1 (0.97) MEN1KMT2ATDP1RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US claimed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US claimed
US-12281180-B2 Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same NEW YORK UNIVERSITY (US) 2025-04-22 US disclosed
US-12133840-B2 Halogenated xanthene composition and method for treating hematologic cancers PROVECTUS PHARMATECH, INC. (US) 2024-11-05 US disclosed
US-20240316191-A1 Halogenated Xanthenes as Vaccine Adjuvants Provectus Pharmatech , Inc. (US) 2024-09-26 US disclosed
US-12064507-B2 Composition and method for oral treatment of leukemia PROVECTUS PHARMATECH, INC. (US) 2024-08-20 US disclosed
US-11975106-B2 Uses of halogenated xanthenes in oncology and virology PROVECTUS PHARMATECH, INC. (US) 2024-05-07 US disclosed
US-11938182-B2 Halogenated xanthenes as vaccine adjuvants PROVECTUS PHARMATECH, INC. (US) 2024-03-26 US disclosed
US-20240082206-A1 Composition and Method for Treating Hematologic Cancers PROVECTUS PHARMATECH, INC. (US) 2024-03-14 US disclosed
EP-3773548-B1 IN VITRO AND XENOGRAFT ANTI-TUMOR ACTIVITY OF A HALOGENATED-XANTHENE AGAINST REFRACTORY PEDIATRIC SOLID TUMORS PROVECTUS PHARMATECH INC (US) 2023-08-09 EP disclosed
US-11561155-B2 Heavy metal ion-hematein-complexes useful as ex vivo contrast agent for a computed tomography scanning of a biological sample, ex vivo method for investigating a biological sample, and use of the complexes Technische Universität München (DE) 2023-01-24 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
WO-2008003954-A1 DYE IMAGING AGENTS GE HEALTHCARE LIMITED (GB) 2008-01-10 WO disclosed
US-7306632-B2 Leave-in color conditioner HAIRMARKER LLC (US) 2007-12-11 US disclosed
US-20050198746-A1 Leave-in color conditioner HAIRMARKER LLC 2005-09-15 US disclosed
WO-1994020850-A1 pH-ZONE-REFINING COUNTERCURRENT CHROMATOGRAPHY THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-09-15 WO disclosed
US-5332504-A Acidification and basification of liquids and centrifuging THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12064507-B2 Composition and method for oral treatment of leukemia MCL1, BCL6, CD47 MEN1 1401/4885KMT2A 2902/4885TDP1 1159/4885
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES FASTKD5, KCNA5, KCNQ5 MEN1 2830/4885KMT2A 291/4885TDP1 2574/4885
US-20240316191-A1 Halogenated Xanthenes as Vaccine Adjuvants IFNG, IRF3, STING1 MEN1 869/4885KMT2A 3435/4885TDP1 725/4885
US-11561155-B2 Heavy metal ion-hematein-complexes useful as ex vivo contrast agent for a computed tomography scanning of a biological sample, ex vivo method for investigating a biological sample, and use of the complexes SERPINC1, CD63, CD68 MEN1 92/4885KMT2A 3751/4885TDP1 4312/4885
US-11938182-B2 Halogenated xanthenes as vaccine adjuvants IFNG, IRF3, STING1 MEN1 869/4885KMT2A 3435/4885TDP1 725/4885
US-20240082206-A1 Composition and Method for Treating Hematologic Cancers BCL6, CD47, ETV6 MEN1 283/4885KMT2A 2677/4885TDP1 1167/4885
US-12133840-B2 Halogenated xanthene composition and method for treating hematologic cancers ETV6, BCL6, XPA MEN1 473/4885KMT2A 2095/4885TDP1 1496/4885
US-11975106-B2 Uses of halogenated xanthenes in oncology and virology IFNG, IRF3, IFNAR1 MEN1 958/4885KMT2A 3072/4885TDP1 943/4885
US-12281180-B2 Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same WNT1, WNT3, WNT3A MEN1 1000/4885KMT2A 4855/4885TDP1 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.