Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500548 | 0.89 | CA1 (0.50) | CA1CA2CA9HPGDSMN1; SMN2 | |
| SCHEMBL3618880 | 0.82 | CA1 (0.50) | CA1CA2CA9HPGDSMN1; SMN2 | |
| SCHEMBL3625424 | 0.81 | CA1 (0.49) | CA1CA2CA9HSD17B10KMT2A | |
| SCHEMBL11228850 | 0.81 | ALDH1A1 (0.51) | CA1CA2CA9HPGDSMN1; SMN2 | |
| SCHEMBL11007887 | 0.81 | TRPV1 (0.61) | SMN1; SMN2HSD17B10KMT2AKDM4EMAPT | |
| SCHEMBL3626340 | 0.79 | HDAC1 (0.55) | CA1CA2CA9SMN1; SMN2HSD17B10 | |
| SCHEMBL6996161 | 0.79 | CA1 (0.55) | CA1CA2CA9SMN1; SMN2HSD17B10 | |
| SCHEMBL29822237 | 0.78 | KDM4E (0.66) | CA1CA2CA9HPGDSMN1; SMN2 | |
| SCHEMBL4311940 | 0.78 | KDM4E (0.66) | CA1CA2CA9HPGDSMN1; SMN2 | |
| SCHEMBL9400181 | 0.78 | RAB9A (0.63) | CA1CA2CA9SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| EP-2174929-A1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-2174929-A1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | CA1 3968/4885CA2 3482/4885CA9 1786/4885 |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | CA1 3968/4885CA2 3482/4885CA9 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.