Pyruvate

Pyruvate

SCHEMBL3626124

C=C/C=C/CC.CC(=O)C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.39
PPARA Q07869 2/20 0.37
ALDH1A1 P00352 4/20 0.33
OXER1 Q8TDS5 3/20 0.33
CYP19A1 P11511 2/20 0.33
RXRA P19793 2/20 0.33
PPARG P37231 2/20 0.33
FFAR1 O14842 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.32
F7 P08709 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
F3 P13726 1/20 0.31
PTGS1 P23219 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARD Q03181 1/20 0.31
GLO1 Q04760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyruvate SCHEMBL3626126 1.00 TRPA1 (0.39) TRPA1PPARAALDH1A1OXER1CYP19A1
Oxalic Acid SCHEMBL27702626 0.91 TRPA1 (0.42) TRPA1PPARAALDH1A1OXER1CYP19A1
Bicarbonate SCHEMBL980471 0.88 TRPA1 (0.43) TRPA1PPARAALDH1A1OXER1CYP19A1
Acrylic Acid SCHEMBL31397813 0.84 LMNA (0.48) TRPA1PPARAALDH1A1OXER1CYP19A1
Fumaric Acid SCHEMBL27832009 0.82 PPARA (0.46) TRPA1PPARAALDH1A1OXER1TSHR
Maleic Acid SCHEMBL28467196 0.82 PPARA (0.46) TRPA1PPARAALDH1A1OXER1TSHR
Bicarbonate SCHEMBL27485028 0.82 TRPA1 (0.39) TRPA1PPARAALDH1A1OXER1CYP19A1
Succinic Acid SCHEMBL27919584 0.82 ALDH1A1 (0.47) TRPA1PPARAALDH1A1OXER1CYP19A1
Urea SCHEMBL27773384 0.81 TRPA1 (0.42) TRPA1PPARAALDH1A1OXER1CYP19A1
SCHEMBL28483961 0.80 TRPA1 (0.37) TRPA1PPARAALDH1A1OXER1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7695863-B2 rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive UBE INDUSTRIES, LTD. (JP) 2010-04-13 US disclosed
US-20080102377-A1 rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive UBE INDUSTRIES, LTD (JP) 2008-05-01 US disclosed