Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 3/20 | 0.34 |
| ▸ | F3 | P13726 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27702626 | 0.92 | TRPA1 (0.42) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| Acrylic Acid SCHEMBL31397813 | 0.90 | LMNA (0.48) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| Pyruvate SCHEMBL3626124 | 0.88 | TRPA1 (0.39) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| Succinic Acid SCHEMBL27919584 | 0.88 | ALDH1A1 (0.47) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| Bicarbonate SCHEMBL27485028 | 0.88 | TRPA1 (0.39) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| Pyruvate SCHEMBL3626126 | 0.88 | TRPA1 (0.39) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| Fumaric Acid SCHEMBL27832009 | 0.88 | PPARA (0.46) | TRPA1ALDH1A1OXER1PPARATSHR | |
| Maleic Acid SCHEMBL28467196 | 0.88 | PPARA (0.46) | TRPA1ALDH1A1OXER1PPARATSHR | |
| Urea SCHEMBL27773384 | 0.87 | TRPA1 (0.42) | TRPA1ALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL28483961 | 0.86 | TRPA1 (0.37) | TRPA1ALDH1A1CYP19A1OXER1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 565 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250349901-A1 | NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY | LG ENERGY SOLUTION LTD (KR) | 2025-11-13 | — | — | US | claimed |
| CN-119890433-A | Flame-retardant polymer electrolyte and preparation method of polymer battery | 路华固态聚合物电池(东莞)有限公司 | 2025-04-25 | — | — | CN | claimed |
| EP-3940845-B1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | NINGDE AMPEREX TECHNOLOGY LTD (CN) | 2025-01-22 | — | — | EP | claimed |
| US-12125983-B2 | Electrolyte and electrochemical device including the same | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2024-10-22 | — | — | US | claimed |
| EP-3940845-A1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | NingDe Amperex Technology Limited (CN) | 2022-01-19 | — | — | EP | claimed |
| EP-4148851-B1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | NINGDE AMPEREX TECHNOLOGY LTD (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-20260094882-A1 | LITHIUM-ION BATTERY | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2026-04-02 | — | — | US | disclosed |
| US-12537184-B2 | Electrochemical device and electronic device | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2026-01-27 | — | — | US | disclosed |
| US-20250372707-A1 | Non-Aqueous Electrolyte and Lithium Secondary Battery Using the Same | LG ENERGY SOLUTION, LTD. (KR) | 2025-12-04 | — | — | US | disclosed |
| EP-4657604-A2 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | Ningde Amperex Technology Limited (CN) | 2025-12-03 | — | — | EP | disclosed |
| EP-4404324-B1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | NINGDE AMPEREX TECHNOLOGY LTD (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-20250349901-A1 | NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY | LG ENERGY SOLUTION LTD (KR) | 2025-11-13 | — | — | US | disclosed |
| EP-2475041-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME | Mitsubishi Chemical Corporation (JP) | 2012-07-11 | — | — | EP | disclosed |
| CN-102484281-A | Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same | MITSUBISHI CHEM CORP | 2012-05-30 | — | — | CN | disclosed |
| US-20110014504-A1 | LITHIUM SECONDARY BATTERY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20090253044-A1 | Nonaqueous Electrolyte and Lithium ion Secondary Battery Using Same | MITSUI CHEMICALS, INC. (JP) | 2009-10-08 | — | — | US | disclosed |
| US-20080311478-A1 | Lithium Secondary Battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-100399107-C | Improved single vision lenses | SOLA INTERNAT HOLDING LTD (AU) | 2008-07-02 | — | — | CN | disclosed |
| EP-1892789-A1 | LITHIUM SECONDARY BATTERY | Mitsubishi Chemical Corporation (JP) | 2008-02-27 | — | — | EP | disclosed |
| CN-1214125-A | Improved simple-to-look lens | SOLA INTERNATIONAL HOLDING LTD (AU) | 1999-04-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12537184-B2 | Electrochemical device and electronic device | LBR, LAMTOR3, CACNA2D1 | TRPA1 1224/4885ALDH1A1 3398/4885CYP19A1 2355/4885 |
| US-20260094882-A1 | LITHIUM-ION BATTERY | LBR, SLC9A2, SLC8A1 | TRPA1 3198/4885ALDH1A1 3938/4885CYP19A1 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.