SCHEMBL3626824

SCHEMBL3626824

CCCCCCCCNC(=O)[C@H](CO)NC(=O)OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 18/20 0.65
SIRT1 Q96EB6 13/20 0.65
SIRT3 Q9NTG7 11/20 0.65
MEN1 O00255 1/20 0.64
ALDH1A1 P00352 1/20 0.64
HPGD P15428 1/20 0.64
KMT2A Q03164 1/20 0.64
CTSL P07711 1/20 0.62
CTSS P25774 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671485 1.00 SIRT2 (0.65) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL9306413 0.99 CTSL (0.64) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL11737428 0.91 CTSL (0.76) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL16601896 0.91 CTSL (0.67) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL20542841 0.89 CAPN1 (0.76) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL20543115 0.89 SIRT2 (0.65) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL13870521 0.89 CAPN1 (0.76) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL20542843 0.89 CAPN1 (0.76) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL20543118 0.89 SIRT2 (0.65) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL7798898 0.89 SIRT2 (0.65) SIRT2SIRT1SIRT3MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700701-B2 Water-soluble polymer compound having sugar chains TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-04-20 US disclosed
US-7700701-B2 Water-soluble polymer compound having sugar chains TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-04-20 US disclosed
US-20060287457-A1 Sugar chain-containing water-soluble polymer compound NISHIMURA, SHIN-ICHIRO, MR. (JP) 2006-12-21 US disclosed
US-6046040-A Method for producing glycoconjugates TOYO BOSEKI KABUSHIKI KAISHA (JP) 2000-04-04 US disclosed
EP-0897014-A2 Method for producing glycoconjugates Toyo Boseki Kabushiki Kaisha (JP) 1999-02-17 EP disclosed