Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.64 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 17/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 11/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.61 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626824 | 0.99 | SIRT2 (0.65) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL671485 | 0.99 | SIRT2 (0.65) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL16601896 | 0.89 | CTSL (0.67) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL11737428 | 0.89 | CTSL (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL13870521 | 0.87 | CAPN1 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20542841 | 0.87 | CAPN1 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20543118 | 0.87 | SIRT2 (0.65) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20543115 | 0.87 | SIRT2 (0.65) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20542843 | 0.87 | CAPN1 (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL7798898 | 0.87 | SIRT2 (0.65) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347007-A | Mesylated hydroxymethyl compound treated with alkali metal chloride or quaternary ammonium chloride to form chloromethylamide compound | E. R. SQUIBB & SONS, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5281716-A | Enzyme inhibitors for anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0575069-A1 | Method for preparing 7-oxabicycloheptyl substituted oxazole amide prostaglandin analog intermediates useful in the preparation of antithrombotic and anti-vasospastic compounds | E.R. Squibb & Sons, Inc. (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5260448-A | Treating a vinyl bromide containing compound with a metal carbonate cyclizing agent | E. R. SQUIBB & SONS, INC. (US) | 1993-11-09 | — | — | US | disclosed |
| US-5260449-A | Method for preparing 7-oxabicycloheptyl substituted bromooxazole amide prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds | E. R. SQUIBB & SONS, INC. (US) | 1993-11-09 | — | — | US | disclosed |