Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589528 | 0.90 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL4275191 | 0.89 | PPARG (0.51) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL16065424 | 0.87 | PPARG (0.59) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL4032384 | 0.85 | PTGS2 (0.54) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL3628841 | 0.85 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL9998913 | 0.84 | THRA (0.44) | PTGS2TSHRTDP1MTNR1AMTNR1B | |
| SCHEMBL12569393 | 0.84 | TAAR1 (0.59) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL5420876 | 0.84 | ALDH1A1 (0.54) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL11600678 | 0.84 | PTGS2 (0.49) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL2350992 | 0.84 | PTGS2 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151546-A | Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | claimed |
| JP-10306126-A | — | — | None | — | — | JP | disclosed |
| US-5929204-A | Process for removing metals from vinylphenol-type polymers | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| JP-H10306126-A | PRODUCTION OF POLY(3-MONO OR 3,5-DIHALOGEN-SUBSTITUTED-4-ACETOXY OR HYDROXYSTYRENE) | HOECHST AG | 1998-11-17 | — | — | JP | disclosed |
| EP-0860451-A1 | Process for removing metals from vinylphenol-type polymers | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |
| WO-1996019433-A1 | PROCESS FOR PREPARING ACETOXYSTYRENE | HOECHST CELANESE CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |
| EP-0544324-B1 | Process for removing metals from vinylphenol polymers | MARUZEN PETROCHEM CO LTD (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5288850-A | Adsorbing on acidic, cationic exchange resin from dissolved polymer | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| US-5274173-A | Process for the production of poly(4-acetoxystyrene) | HOECHST CELANESE CORPORATION (US) | 1993-12-28 | — | — | US | disclosed |
| US-5274174-A | Process for the production of poly(4-hydroxystyrene) | HOECHST CELANESE CORPORATION (US) | 1993-12-28 | — | — | US | disclosed |
| US-5274175-A | Process for the preparation of 4-acetoxyphenylmethyl carbinol | HOECHST CELANESE CORPORATION (US) | 1993-12-28 | — | — | US | disclosed |
| US-5245074-A | Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products | CLARIANT AG (CH) | 1993-09-14 | — | — | US | disclosed |
| EP-0544324-A1 | Process for removing metals from vinylphenol polymers | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-5151546-A | Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| EP-0449603-A1 | Production of 4-hydroxyphenethyl alcohol | HOECHST CELANESE CORPORATION (US) | 1991-10-02 | — | — | EP | disclosed |
| US-5003115-A | Epoxidation of acetoxystyrene with a percarboxylic acid to produce acetoxyphenyl oxirane, hydrogenation followed by saponification | HOECHST CELANESE CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |