Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629043 | 1.00 | PTPN22 (0.32) | PTPN22NPSR1MAPTMEN1KMT2A | |
| SCHEMBL3627665 | 0.82 | FFAR1 (0.37) | PTPN22NPSR1MEN1KMT2APTPN1 | |
| SCHEMBL3627662 | 0.81 | FFAR1 (0.42) | PTPN22NPSR1MAPTMEN1KMT2A | |
| SCHEMBL6009129 | 0.79 | FFAR1 (0.45) | PTPN22MAPTMEN1KMT2APTPN1 | |
| SCHEMBL6009122 | 0.79 | FFAR1 (0.45) | PTPN22MAPTMEN1KMT2APTPN1 | |
| SCHEMBL3632754 | 0.75 | FFAR1 (0.39) | PTPN22FFAR1 | |
| SCHEMBL3632751 | 0.75 | FFAR1 (0.39) | PTPN22FFAR1 | |
| SCHEMBL6007749 | 0.73 | FFAR1 (0.43) | PTPN22MAPTMEN1KMT2APTPN1 | |
| SCHEMBL6007745 | 0.72 | FFAR1 (0.46) | PTPN22MAPTMEN1KMT2APTPN1 | |
| SCHEMBL3502256 | 0.70 | NLRP3 (0.36) | PTPN22NPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786165-B2 | Aminophenylpropanoic acid derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | GPR119, GPR55, GPR65 | PTPN22 256/4885NPSR1 195/4885MAPT 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.