Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SI | P14410 | 4/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363288 | 0.89 | GPBAR1 (0.39) | GAACHRNA7CA1CA2CA9 | |
| SCHEMBL365294 | 0.85 | GPBAR1 (0.35) | GAACHRNA7CA1CA2CA9 | |
| SCHEMBL12505663 | 0.85 | MGAM (0.41) | MGAMGAASIMGAM2 | |
| SCHEMBL364331 | 0.85 | MGAM (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL362297 | 0.83 | MGAM (0.38) | MGAMGAASIMGAM2 | |
| SCHEMBL365670 | 0.81 | L3MBTL1 (0.40) | MGAMGAASIMGAM2 | |
| SCHEMBL1390421 | 0.81 | CHRNA7 (0.39) | CHRNA7CA1CA2CA9CA12 | |
| SCHEMBL364467 | 0.78 | GPBAR1 (0.39) | GAACHRNA7CA1CA2CA9 | |
| SCHEMBL363176 | 0.78 | GPBAR1 (0.39) | GAACHRNA7CA1CA2CA9 | |
| SCHEMBL363016 | 0.78 | GPBAR1 (0.39) | GAACHRNA7CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |