Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | SI | P14410 | 5/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361734 | 0.88 | GPBAR1 (0.34) | KDM4ELMNABRD4IDH1GPR27 | |
| SCHEMBL364331 | 0.85 | MGAM (0.43) | MGAMGAASIMGAM2BRD4 | |
| SCHEMBL365670 | 0.84 | L3MBTL1 (0.40) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL12505663 | 0.84 | MGAM (0.41) | MGAMGAASIMGAM2BRD4 | |
| SCHEMBL362955 | 0.83 | MGAM (0.38) | MGAMGAASIMGAM2 | |
| SCHEMBL370270 | 0.82 | POLB (0.38) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL1390555 | 0.81 | KDM4E (0.38) | KDM4ELMNABRD4IDH1GPR27 | |
| SCHEMBL1390603 | 0.76 | EPHX2 (0.48) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL363551 | 0.76 | EGFR (0.35) | MGAMGAASIMGAM2KCNH2 | |
| SCHEMBL364598 | 0.75 | ALDH1A1 (0.38) | MGAMGAASIMGAM2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |