Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | SI | P14410 | 7/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505663 | 0.92 | MGAM (0.41) | MGAMGAASIMGAM2POLB | |
| SCHEMBL365670 | 0.90 | L3MBTL1 (0.40) | MGAMGAASIMGAM2POLB | |
| SCHEMBL365274 | 0.88 | GPBAR1 (0.46) | MGAMGAASIMGAM2POLB | |
| SCHEMBL363934 | 0.86 | GPBAR1 (0.47) | MGAMGAASIMGAM2POLB | |
| SCHEMBL363178 | 0.85 | GPBAR1 (0.51) | MGAMGAASIMGAM2POLB | |
| SCHEMBL362297 | 0.85 | MGAM (0.38) | MGAMGAASIMGAM2POLB | |
| SCHEMBL362955 | 0.85 | MGAM (0.38) | MGAMGAASIMGAM2 | |
| SCHEMBL14894610 | 0.83 | GPBAR1 (0.52) | MGAMGAASIMGAM2BRD4 | |
| SCHEMBL370270 | 0.82 | POLB (0.38) | MGAMGAASIMGAM2POLB | |
| SCHEMBL369868 | 0.80 | KMT2A (0.47) | MGAMGAASIMGAM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |