Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364975 | 0.82 | GPBAR1 (0.30) | — | |
| SCHEMBL362087 | 0.79 | ALDH1A1 (0.31) | KCNN4ALDH1A1RAB9A | |
| SCHEMBL365351 | 0.75 | CYP19A1 (0.31) | KCNN4 | |
| SCHEMBL363274 | 0.73 | NPC1 (0.35) | KCNN4RAB9A | |
| SCHEMBL365534 | 0.73 | NPC1 (0.35) | KCNN4RAB9A | |
| SCHEMBL364627 | 0.73 | NPC1 (0.35) | KCNN4RAB9A | |
| SCHEMBL364476 | 0.72 | NFE2L2 (0.33) | — | |
| SCHEMBL3523097 | 0.71 | KCNN4 (0.43) | KCNN4ALDH1A1 | |
| SCHEMBL3523100 | 0.71 | KCNN4 (0.43) | KCNN4ALDH1A1 | |
| SCHEMBL364097 | 0.69 | TRPA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |