SCHEMBL3629797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3624614	0.83	TYMS (0.47)	KDM4EALDH1A1HPGDBRD4GAA
	SCHEMBL15287086	0.83	ALDH1A1 (0.42)	KDM4EALDH1A1HPGDBRD4GAA
	SCHEMBL16532787	0.82	ALDH1A1 (0.38)	KDM4EALDH1A1HPGDBRD4GAA
	SCHEMBL17917426	0.78	ALDH1A1 (0.38)	ALDH1A1HPGDBRD4GAAKMT2A
	SCHEMBL3631135	0.78	ALDH1A1 (0.43)	ALDH1A1BRD4GAAKMT2AMEN1
	SCHEMBL16193429	0.78	HTR1A (0.50)	KDM4EALDH1A1HPGDBRD4GAA
	SCHEMBL16532792	0.77	ALDH1A1 (0.34)	KDM4EALDH1A1HPGDGAATYMS
	SCHEMBL15286902	0.76	FFAR1 (0.46)	—
	SCHEMBL17917429	0.76	FFAR1 (0.41)	ALDH1A1GAATYMSPDE4DS1PR1
	SCHEMBL4065877	0.76	ALDH1A1 (0.43)	KDM4EALDH1A1HPGDGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.