Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867018 | 0.84 | KDM4E (0.47) | FLT3CA2DAOKDM4EPDPK1 | |
| SCHEMBL4629425 | 0.82 | FLT3 (0.38) | FLT3CA2DAOKDM4EPDPK1 | |
| SCHEMBL3633471 | 0.76 | MEN1 (0.44) | DAOKDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL4629545 | 0.71 | VCP (0.47) | KDM4E | |
| Hydrochloric Acid SCHEMBL4628914 | 0.71 | VCP (0.46) | KDM4E | |
| SCHEMBL69135 | 0.70 | CA2 (0.61) | CA2ALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL31146723 | 0.70 | CA2 (0.61) | CA2ALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL10340796 | 0.70 | CA2 (0.61) | CA2ALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL4263897 | 0.69 | CA2 (0.40) | CA2DAOKDM4EALDH1A1AKR1B1 | |
| SCHEMBL10587183 | 0.68 | CA2 (0.59) | CA2ALDH1A1LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155674-A1 | AMINOALKOXY ARYL SULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008136017-A1 | AMINOALKOXY ARYL SULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-11-13 | — | — | WO | disclosed |