Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 6/20 | 0.47 |
| ▸ | HTR6 | P50406 | 7/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4628914 | 0.99 | VCP (0.46) | VCPHTR6HRH4KDM4EHTR2A | |
| SCHEMBL4630173 | 0.88 | HRH4 (0.45) | VCPHTR6HRH4HTR2AHTR2C | |
| SCHEMBL4630178 | 0.88 | HTR6 (0.44) | VCPHTR6HRH4HTR2A | |
| SCHEMBL4630016 | 0.87 | CA2 (0.46) | VCPHTR6HRH4KDM4E | |
| SCHEMBL4724711 | 0.86 | VCP (0.41) | VCPHTR6HRH4HTR2AHTR2C | |
| SCHEMBL4762974 | 0.85 | VCP (0.41) | VCPHTR6HRH4HTR2AHTR2C | |
| SCHEMBL4630008 | 0.85 | HTR6 (0.42) | HTR6HRH4KDM4E | |
| SCHEMBL4628917 | 0.83 | VCP (0.48) | VCPHTR6HRH4HTR2AHTR2C | |
| SCHEMBL4762174 | 0.83 | MAPT (0.43) | VCPHRH4KDM4E | |
| SCHEMBL4629550 | 0.82 | POLB (0.44) | HTR6HRH4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | claimed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |