Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713056 | 0.91 | RORC (0.56) | LMNAPOLBKCNMA1ALDH1A1MEN1 | |
| SCHEMBL28098625 | 0.90 | LMNA (0.54) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL13798207 | 0.88 | RECQL (0.62) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL257135 | 0.86 | LMNA (0.61) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL48961 | 0.86 | MRGPRX4 (0.64) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL30100412 | 0.86 | MRGPRX4 (0.64) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL6542484 | 0.86 | LMNA (0.61) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL364764 | 0.86 | ALDH1A1 (0.65) | LMNAPOLBKCNMA1ALDH1A1MAPT | |
| SCHEMBL6103175 | 0.86 | POLB (0.66) | LMNAPOLBALDH1A1MAPTTSHR | |
| SCHEMBL5990108 | 0.86 | NPC1 (0.53) | LMNAPOLBKCNMA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251546-A | Process for killing internal helminths using certain 1,1-bis-(2-substituted-3-nitrophenyl)alkane or alkylene derivatives | ICI AUSTRALIA LIMITED (AU) | 1981-02-17 | — | — | US | disclosed |