Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195746 | 0.84 | SMN1; SMN2 (0.42) | KDM1AMAOBSLC6A7FASN | |
| SCHEMBL5160130 | 0.78 | RAB9A (0.37) | KDM1AALDH1A1 | |
| SCHEMBL3665330 | 0.74 | ALDH1A1 (0.41) | DPP4ALDH1A1 | |
| SCHEMBL3623060 | 0.73 | GHSR (0.43) | USP30FASN | |
| SCHEMBL2320538 | 0.63 | MAOA (0.40) | KDM1AMAOBALDH1A1HRH3 | |
| SCHEMBL1966806 | 0.63 | POLB (0.47) | ALDH1A1 | |
| SCHEMBL16649636 | 0.63 | MAOA (0.41) | MAOBALDH1A1 | |
| SCHEMBL14813594 | 0.63 | MAOA (0.41) | KDM1AMAOBALDH1A1 | |
| SCHEMBL22680582 | 0.63 | FASN (0.49) | KDM1AUSP30ALDH1A1FASN | |
| SCHEMBL28111674 | 0.63 | CYP2A6 (0.42) | KDM1AMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142505-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008120093-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 2008-10-09 | — | — | WO | disclosed |