Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396111 | 0.98 | KMT2A (0.43) | KMT2AMEN1MAPTPTK2BLMNA | |
| SCHEMBL28535131 | 0.97 | KMT2A (0.42) | KMT2AMEN1MAPTPTK2BLMNA | |
| SCHEMBL7164936 | 0.83 | MEN1 (0.54) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL6243396 | 0.76 | CYP19A1 (0.46) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL8370090 | 0.76 | KMT2A (0.57) | KMT2AMAPTLMNATTRAKR1B10 | |
| SCHEMBL7759545 | 0.76 | HTT (0.45) | KMT2ALMNARAB9ATTRAKR1B10 | |
| SCHEMBL6243149 | 0.76 | MEN1 (0.51) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL8365425 | 0.76 | KMT2A (0.50) | KMT2AMEN1LMNATTRAKR1B10 | |
| SCHEMBL27926510 | 0.74 | CYP19A1 (0.47) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL16672098 | 0.73 | KMT2A (0.58) | KMT2AMEN1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4245752-A2 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | Techfields Inc (US) | 2023-09-20 | — | — | EP | disclosed |
| CN-116350597-A | Preparation method of diclofenac sodium sustained-release preparation | 珠海润都制药股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113237976-B | Method for detecting impurities in diclofenac sodium | 珠海润都制药股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115704805-A | Method for detecting content of diclofenac sodium in diclofenac sodium preparation and related substances | 珠海润都制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| EP-2170826-B1 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | TECHFIELDS INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-20210353579-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO LTD (CN) | 2021-11-18 | — | — | US | disclosed |
| CN-113402408-A | Method for synthesizing diclofenac sodium | 河南康达制药有限公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-113237976-A | Method for detecting impurities in diclofenac sodium | 珠海润都制药股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-111100057-B | Method for synthesizing diclofenac sodium intermediate 1- (2, 6-dichlorophenyl) indoline-2-ketone | 天方药业有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111116391-A | Preparation method of sodium 2- [ (2, 6-dichlorophenyl) amino ] phenylacetate | 浙江工业大学 | 2020-05-08 | — | — | CN | disclosed |
| WO-2008012602-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF DICLOFENAC WITH VERY FAST SKIN PENETRATION RATE | TECHFIELDS BIOCHEM CO. LTD (CN) | 2008-01-31 | — | — | WO | disclosed |
| CN-1276750-C | Diclofenac sodium oral pharmaceutical | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2006-09-27 | — | — | CN | disclosed |
| US-20050214360-A1 | Diclofenac sodium oral pharmaceutical | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2005-09-29 | — | — | US | disclosed |
| CN-1642539-A | Diclofenac sodium oral pharmaceutical | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2005-07-20 | — | — | CN | disclosed |
| EP-1154999-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000051988-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2000-09-08 | — | — | WO | disclosed |
| EP-0735865-B1 | EXPULSION OF MATERIAL FROM A DELIVERY DEVICE | SCHERER CORP R P (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5897874-A | DEVICE COMPRISING WATER IMPERMEABLE HOLLOW BODY CONTAINING SUBSTANCE TO BE DELIVERED AND EXPANDABLE MATERIAL, WATER SWELLABLE PLUG ENGAGED WITH NECK PORTION WHICH SWELLS AND DISENGAGES IN AQUEOUS MEDIUM | R. P. SCHERER CORPORATION (US) | 1999-04-27 | — | — | US | disclosed |
| EP-0735865-A1 | EXPULSION OF MATERIAL FROM A DELIVERY DEVICE | R.P. SCHERER CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017172-A1 | EXPULSION OF MATERIAL FROM A DELIVERY DEVICE | R.P. SCHERER CORPORATION (US) | 1995-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353579-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | KMT2A 3616/4885MEN1 4272/4885MAPT 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.