Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109810 | 0.89 | LMNA (0.33) | HTTKDM4EHPGDTP53 | |
| SCHEMBL3110825 | 0.87 | TDP1 (0.34) | HTTKDM4EALDH1A1GAATP53 | |
| SCHEMBL871002 | 0.87 | KMT2A (0.36) | HTTKDM4EALDH1A1 | |
| SCHEMBL1035116 | 0.86 | ALDH1A1 (0.39) | HTTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL1036065 | 0.86 | PDK2 (0.36) | HPGDTP53 | |
| SCHEMBL21863693 | 0.85 | PDK2 (0.39) | HPGD | |
| SCHEMBL3110768 | 0.85 | PSMB11 (0.34) | KDM4EALDH1A1GAATP53 | |
| SCHEMBL3115589 | 0.85 | POLR1A (0.34) | POLBKDM4ETP53 | |
| SCHEMBL3110292 | 0.85 | PSMB11 (0.34) | KDM4EALDH1A1GAATP53 | |
| SCHEMBL16687347 | 0.84 | ORAI1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158188-A2 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. Du Pont de Nemours and Company (US) | 2010-03-03 | — | — | EP | disclosed |
| WO-2009002809-A2 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |