Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110825 | 0.95 | TDP1 (0.34) | LMNASMN1; SMN2TP53KDM4EHTT | |
| SCHEMBL3115305 | 0.94 | MEN1 (0.32) | — | |
| SCHEMBL3110152 | 0.93 | NPC1 (0.32) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3101015 | 0.90 | LMNA (0.31) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL871002 | 0.90 | KMT2A (0.36) | KDM4EHTT | |
| SCHEMBL1035116 | 0.89 | ALDH1A1 (0.39) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1036065 | 0.89 | PDK2 (0.36) | LMNAHPGDTP53 | |
| SCHEMBL3637389 | 0.89 | POLB (0.32) | HPGDTP53KDM4EHTT | |
| SCHEMBL3115589 | 0.88 | POLR1A (0.34) | LMNAL3MBTL1TP53KDM4E | |
| SCHEMBL3110847 | 0.87 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222618-B1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3222618-A1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-2158188-B1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2017-04-26 | — | — | EP | disclosed |
| US-9095138-B2 | Isoxazoline insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150098928-A9 | ISOXAZOLINE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-09 | — | — | US | disclosed |
| US-20140127165-A1 | ISOXAZOLINE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2014-04-24 | — | — | US | disclosed |
| US-8623875-B2 | Isoxazoline insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2155701-B1 | ISOXAZOLINE INSECTICIDES | DU PONT (US) | 2013-12-11 | — | — | EP | disclosed |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | DU PONT (US) | 2013-08-22 | — | — | US | disclosed |
| US-8410153-B2 | Naphthalene isoxazoline invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100179195-A1 | ISOXAZOLINE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2010-07-15 | — | — | US | disclosed |
| EP-2158188-A2 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. Du Pont de Nemours and Company (US) | 2010-03-03 | — | — | EP | disclosed |
| WO-2009002809-A2 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | C1S, C1R, C9 | LMNA 777/4885NPC1 266/4885RAB9A 1701/4885 |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | C1S, C1R, C9 | LMNA 777/4885NPC1 266/4885RAB9A 1701/4885 |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | C1S, C1R, C9 | LMNA 777/4885NPC1 266/4885RAB9A 1701/4885 |
| US-20150098928-A9 | ISOXAZOLINE INSECTICIDES | CBR3, CYP4X1, PRDX1 | LMNA 3243/4885NPC1 1154/4885RAB9A 1906/4885 |
| US-20140127165-A1 | ISOXAZOLINE INSECTICIDES | CBR3, CYP4X1, PRDX1 | LMNA 3243/4885NPC1 1154/4885RAB9A 1906/4885 |
| US-20100179195-A1 | ISOXAZOLINE INSECTICIDES | CBR3, CYP4X1, PRDX1 | LMNA 3243/4885NPC1 1154/4885RAB9A 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.