SCHEMBL363907

SCHEMBL363907

CCOC(=O)CC(=O)NN

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.64
MGAM O43451 1/20 0.64
SI P14410 1/20 0.64
MGAM2 Q2M2H8 1/20 0.64
ALDH1A1 P00352 5/20 0.46
CTSD P07339 1/20 0.46
TRPA1 O75762 1/20 0.46
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.44
ALOX15 P16050 1/20 0.44
PKM P14618 2/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 2/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4937611 0.82 CTSD (0.54) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL23326643 0.79 GAA (0.68) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331187 0.79 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8636 0.79 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1330550 0.79 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1864301 0.79 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331824 0.79 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11417237 0.79 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL5382123 0.79 CYP1A2 (0.59) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL4588694 0.78 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11398630-B2 Method of generating energy from a hydrazide containing anode fuel, and fuel cell IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-26 US claimed
CN-113387834-A Continuous synthesis method of 3-oxo-3-hydrazino ethyl propionate 苏州工业园区服务外包职业学院 2021-09-14 CN claimed
US-20210005900-A1 METHOD OF GENERATING ENERGY FROM A HYDRAZIDE CONTAINING ANODE FUEL, AND FUEL CELL IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-01-07 US claimed
US-20260097034-A1 METALLOENZYME INHIBITOR COMPOUNDS CORXEL PHARMACEUTICALS HONG KONG LTD (HK) 2026-04-09 US disclosed
US-12458642-B2 Metalloenzyme inhibitor compounds CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) 2025-11-04 US disclosed
US-12391690-B2 Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same LIGACHEM BIOSCIENCES INC. (KR) 2025-08-19 US disclosed
WO-2024222866-A1 CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2024-10-31 WO disclosed
EP-4323066-A1 MEK INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2024-02-21 EP disclosed
CN-117580835-A MEK inhibitors and uses thereof 医肯纳肿瘤学公司 2024-02-20 CN disclosed
EP-4311577-A2 METALLOENZYME INHIBITOR COMPOUNDS Ji Xing Pharmaceuticals Hong Kong Limited (HK) 2024-01-31 EP disclosed
EP-3562487-B1 METALLOENZYME INHIBITOR COMPOUNDS JI XING PHARMACEUTICALS HONG KONG LTD (HK) 2023-11-29 EP disclosed
US-20050208582-A1 Pyrazole compounds and pharmaceutical compositions comprising the compound EISAI R&D MANAGEMENT CO., LTD. (JP) 2005-09-22 US disclosed
US-20050124605-A1 Novel benzo-fused heterocycles as endothelin antagonisits ACTELION PHARMACEUTICALS LTD. 2005-06-09 US disclosed
EP-1510516-A1 PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME Eisai Co., Ltd. (JP) 2005-03-02 EP disclosed
CN-1538848-A Novel Benzo-fused heterocycles ������˹ҩƷ��˾ 2004-10-20 CN disclosed
WO-2003013545-A1 NOVEL BENZO-FUSED HETEROCYCLES AS ENDOTHELIN ANTAGONISITS ACTELION PHARMACEUTICALS LTD (CH) 2003-02-20 WO disclosed
WO-2000066573-A2 OXA COMBINATORIAL LIBRARY, PRODUCTION AND USE THEREOF CEREP (FR) 2000-11-09 WO disclosed
EP-0409840-A4 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES 1991-09-04 EP disclosed
EP-0409840-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-01-30 EP disclosed
WO-1990009369-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124605-A1 Novel benzo-fused heterocycles as endothelin antagonisits EDNRA, EDNRB, ECE1 GAA 2736/4885MGAM 4811/4885SI 3104/4885
US-12458642-B2 Metalloenzyme inhibitor compounds CYP11B2, CYP11B1, HSD11B2 GAA 139/4885MGAM 416/4885SI 451/4885
US-12391690-B2 Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same ENPP2, PLA2G10, LPCAT1 GAA 1678/4885MGAM 4033/4885SI 1995/4885
US-20260097034-A1 METALLOENZYME INHIBITOR COMPOUNDS CPN1, TPP1, DPP4 GAA 5/4885MGAM 119/4885SI 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.