Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364331 | 0.82 | MGAM (0.43) | POLBMGAMGAASIMGAM2 | |
| SCHEMBL362297 | 0.82 | MGAM (0.38) | POLBLMNAMGAMGAASI | |
| SCHEMBL1390435 | 0.82 | LDHA (0.40) | POLBLMNASMN1; SMN2CASP3ALDH1A1 | |
| SCHEMBL365670 | 0.81 | L3MBTL1 (0.40) | POLBLMNAALDH1A1MGAMGAA | |
| SCHEMBL12505663 | 0.81 | MGAM (0.41) | POLBSMN1; SMN2MGAMGAASI | |
| SCHEMBL362955 | 0.76 | MGAM (0.38) | MGAMGAASIMGAM2 | |
| SCHEMBL365274 | 0.73 | GPBAR1 (0.46) | POLBMGAMGAASIMGAM2 | |
| SCHEMBL361734 | 0.73 | GPBAR1 (0.34) | LMNAMEN1KMT2A | |
| SCHEMBL362064 | 0.73 | CNR1 (0.37) | POLB | |
| SCHEMBL364598 | 0.72 | ALDH1A1 (0.38) | POLBSMN1; SMN2ALDH1A1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |