Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477452 | 0.92 | GAA (0.44) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL30019534 | 0.82 | CA12 (0.43) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL10875748 | 0.80 | AGXT (0.45) | ALDH1A1MAPTKDM4ECA12CA1 | |
| Sulfuric Acid SCHEMBL28117445 | 0.80 | GAA (0.63) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL672184 | 0.78 | APP (0.42) | ALDH1A1MAPTCA12CA1CA2 | |
| Sulfuric Acid SCHEMBL28619661 | 0.76 | APP (0.41) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL10700693 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Sulfuric Acid SCHEMBL28952576 | 0.75 | CA2 (0.59) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL22499933 | 0.74 | GAA (0.62) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Sulfuric Acid SCHEMBL2484445 | 0.73 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTKDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870135-A2 | Brightening and/or dyeing agent with acetamidines | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-12-26 | — | — | EP | claimed |
| EP-2173314-A2 | VAPORIZER SOLUTION, AND DYEING METHOD | Henkel AG & Co. KGaA (DE) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009019049-A2 | VAPORIZER SOLUTION, AND DYEING METHOD | HENKEL AG & CO. KGAA (DE) | 2009-02-12 | — | — | WO | disclosed |